S-nitrosylation of B23/nucleophosmin by GAPDH protects cells from the SIAH1–GAPDH death cascade
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چکیده
منابع مشابه
S-nitrosylation of B23/nucleophosmin by GAPDH protects cells from the SIAH1–GAPDH death cascade
B23/nucleophosmin is a multifunctional protein that participates in cell survival signaling by shuttling between the nucleolus/nucleoplasm and nucleus/cytoplasm. In this paper, we report a novel neuroprotective function of B23 through regulation of the SIAH1-glyceraldehyde-3-phosphate dehydrogenase (GAPDH) death cascade. B23 physiologically bound to both SIAH1 and GAPDH, disrupting the SIAH1-GA...
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ژورنال
عنوان ژورنال: Journal of Cell Biology
سال: 2012
ISSN: 1540-8140,0021-9525
DOI: 10.1083/jcb.201205015